selenium side effects

Kidney damage in people with diabetes (diabetic nephropathy). Pancreatic cancer. Additionally, some researchers say that selenium supplements will reduce the side effects of radiotherapy patients. J Androl 2001;22:764-72.. View abstract. Mego, M., Koncekova, R., Mikuskova, E., Drgona, L., Ebringer, L., Demitrovicova, L., Nemova, I., Trupl, J., Mardiak, J., Koza, I., and Zajac, V. Prevention of febrile neutropenia in cancer patients by probiotic strain Enterococcus faecium M-74. View abstract. The apparent effect of iron supplementation on serum selenium levels in teenage pregnancy. A., Mandaliya, K., Emery, S., Lavreys, L., Ndinya-Achola, J. O., Bankson, D. D., Bwayo, J. J., and Kreiss, J. K. Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial. A systematic review and meta-analysis of population-based prospective studies. J Trace Elem.Med Biol. View abstract. Can J Vet Res 1986;50:297-306. Thyroid 2010;20:1163-73. J Clin Gastroenterol 2001;32:405-8. View abstract. HIV/AIDS. 2018 Sep;33(9):789-810. View abstract. Wilderness.Environ.Med. A., Rusakova, N. E., Larmane, L. T., Karpov, IuG, Ivanov, A. D., and Maulins, E. [Assessment of some oxidative stress parameters in bronchial asthma patients beyond add-on selenium supplementation]. AIDS 1999;13:495-500. View abstract. J Ren Nutr. Li H, Stampfer MJ, Giovannucci EL, et al. View abstract. J Clin Endocrinol Metab 2002;87:1687-91.. View abstract. View abstract. Nutrition 1994;10(4):327-334. Cancer Epidemiol.Biomarkers Prev. PLoS One. Available at: https://wayback.archive-it.org/7993/20171114183712/https://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm168527.htm. View abstract. Biol.Trace Elem.Res. Przegl.Lek. How to Take Control of Treatment Side Effects, Coronary artery bypass graft (CABG) surgery. Selenium is not produced in the body, but it is needed for proper thyroid and immune system function. View abstract. J Natl Cancer Inst 1986;77:299-303. The declaration of nutrition, health, and intelligence for the child-to-be. Burbano, X., Miguez-Burbano, M. J., McCollister, K., Zhang, G., Rodriguez, A., Ruiz, P., Lecusay, R., and Shor-Posner, G. Impact of a selenium chemoprevention clinical trial on hospital admissions of HIV-infected participants. View abstract. Toulis KA, Anastasilakis AD, Tzellos TG, et al. Toxicolog Sci 2000;57:22-31. Stevic, Z., Nicolic, A., and Blagojevic, D. A controlled trial of combination of methionine and antioxidants in ALS patients. Effect of Selenium Supplementation on Glycemic Control and Lipid Profiles in Patients with Diabetic Nephropathy. View abstract. Digestion 1998;59(2):148-156. View abstract. Benton, D. Selenium intake, mood and other aspects of psychological functioning. Chin Med.J.(Engl.) Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. View abstract. Selenium overview for health professionals. Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT. Contempre B, Dumont JE, Ngo B, et al. 12-15-2004;37(5):1657-1663. Early research in China suggests that taking selenium for 2-5 years can reduce the occurrence of liver cancer. Jie KG, Bots ML, Vermeer C, et al. 1997;16(4):357-365. Mishra, V., Baines, M., Perry, S. E., McLaughlin, P. J., Carson, J., Wenstone, R., and Shenkin, A. 2008;(3):CD004183. 2004;52(1):20-24. 2017;102(11):4333-4341. An Italian multicenter double-blinded randomized study between single or combination therapy (PROCOMB trial). Qualified Health Claim: Final Decision Letter on Selenium and Certain Cancers (Docket No. Arch Dis Child Fetal Neonatal Ed 1996;74(3):F158-F164. Balaz C, Feher J. Delmas-Beauvieux, M. C., Peuchant, E., Couchouron, A., Constans, J., Sergeant, C., Simonoff, M., Pellegrin, J. L., Leng, B., Conri, C., and Clerc, M. The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. Review. Lloyd B, Lloyd RS, Clayton BE. Pan, S. Y., Ugnat, A. M., Mao, Y., Wen, S. W., and Johnson, K. C. A case-control study of diet and the risk of ovarian cancer. Biol Trace Elem Res. Schwingshackl L, Boeing H, Stelmach-Mardas M, et al. Clinical and laboratory chemistry infection markers during administration of selenium]. View abstract. Critical illness (trauma). The amount of medicine that you take depends on the strength of the medicine. View abstract. Zhonghua Yu Fang Yi.Xue.Za Zhi. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others. View abstract. Am J Clin Nutr 2008;87:370-8. View abstract. Am.J Clin.Nutr. Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy. Other research suggests that selenium, taken alone or with other nutrients, does not reduce the risk of death. View abstract. Am.J Clin.Nutr. Crit Care Med 2007;35(1):118-126. Colon cancer, rectal cancer. Shaheen, S. O., Newson, R. B., Rayman, M. P., Wong, A. P., Tumilty, M. K., Phillips, J. M., Potts, J. F., Kelly, F. J., White, P. T., and Burney, P. G. Randomised, double blind, placebo-controlled trial of selenium supplementation in adult asthma. Alexander, J. Selenium. View abstract. View abstract. View abstract. Am J Clin Nutr 1993;57:271S-5S. View abstract. Berger MM, Reymond MJ, Shenkin A, et al. Robinson MF, Thomson CD, Jenkinson CP, et al Long-term supplementation with selenate and selenomethionine: urinary excretion by New Zealand women. Prostate cancer. Cancer Epidemiol Biomarkers Prev 1998;7:853-6. J Trace Elem.Med Biol. Ogawa, A., Ogawa, I., Obayashi, R., Umezu, K., Doi, M., and Hirao, T. Highly Selective Thioselenation of Vinylcyclopropanes with a (PhS)(2)-(PhSe)(2) Binary System and Its Application to Thiotelluration. Vinceti M, Filippini T, Rothman KJ. View abstract. Galan, P., Preziosi, P., Monget, A. L., Richard, M. J., Arnaud, J., Lesourd, B., Girodon, F., Alferez, M. J., Bourgeois, C., Keller, H., Favier, A., and Hercberg, S. Effects of trace element and/or vitamin supplementation on vitamin and mineral status, free radical metabolism and immunological markers in elderly long term-hospitalized subjects. View abstract. vitamins, herbal supplements, etc. 2009;20(1):106-111. Effect of very-low-dose naicin on high-density lipoprotein in patients undergoing long-term statin therapy. J Org.Chem. J Androl 2009;30(5):525-533. Heinle, K., Adam, A., Gradl, M., Wiseman, M., and Adam, O. View abstract. Interactions of selenium compounds with other antioxidants in DNA damage and apoptosis in human normal keratinocytes. View abstract. Am.J Clin.Nutr. Pakdaman, A. Symptomatic treatment of brain tumor patients with sodium selenite, oxygen, and other supportive measures. Taking selenium daily during pregnancy seems to reduce the risk of developing thyroid dysfunction after pregnancy and permanent hypothyroidism. Cancer Epidemiol Biomarkers Prev 2002;11:630-9.. View abstract. Most research shows that taking selenium does not reduce the risk of cancer or cancer-related death. View abstract. View abstract. View abstract. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Rao CV, Wang CQ, Simi B, et al. Li YF, Dong Z, Chen C, et al. Trafikowska U, Zachara BA, Wiacek M, et al. How to use safely at dosages lower than 400 mcg per day. View abstract. View abstract. View abstract. View abstract. View abstract. Mego, M., Ebringer, L., Drgona, L., Mardiak, J., Trupl, J., Greksak, R., Nemova, I., Oravcova, E., Zajac, V., and Koza, I. El-Bayoumy K. The protective role of selenium on genetic damage and on cancer. View abstract. View abstract. Muecke R, Micke O, Schomburg L, et al. 2004;13(9):1521-1527. View abstract. Nutritional, toxicologic, and clinical aspects. 2003;22(2):147-156. This survey is being conducted by the WebMD marketing sciences department. Alehagen U, Alexander J, Aaseth J. Supplementation with selenium and coenzyme Q10 reduces cardiovascular mortality in elderly with low selenium status. Support.Care Cancer 2006;14(3):285-290. 2004;151(1):47-54. Along with its needed effects, selenium may cause some unwanted effects. J Clin Oncol 2013;31(33):4179-87. Combs, G. F., Jr., Clark, L. C., and Turnbull, B. W. Reduction of cancer risk with an oral supplement of selenium. However, other research suggests that it has no benefit. Cancer Epidemiol.Biomarkers Prev. Sedative medications (Barbiturates) interacts with SELENIUM. Effects of captopril and enalapril on zinc metabolism in hypertensive patients. Pais R, Dumitrascu DL. View abstract. King JC. Aliment.Pharmacol.Ther. Medically reviewed by Drugs.com. View abstract. Angstwurm, M. W., Schopohl, J., and Gaertner, R. Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients. J Gastroenterol 2013;48(6):698-705. Reasons for the conflicting findings are not clear. Thyroid function parameters during a selenium repletion/depletion study in phenylketonuric subjects. J Environ.Pathol.Toxicol.Oncol. View abstract. Some research suggests that taking yeast enriched with 200 mcg of selenium does not improve RA. View abstract. View abstract. Plasma trace element, plasma glutathione peroxidase, and superoxide dismutase levels in epileptic children receiving antiepileptic drug therapy. Are some major in vivo effects of gold related to microenvironments of decreased selenium? J Rheumatol 1987;14:1104-7. Bardia, A., Tleyjeh, I. M., Cerhan, J. R., Sood, A. K., Limburg, P. J., Erwin, P. J., and Montori, V. M. Efficacy of antioxidant supplementation in reducing primary cancer incidence and mortality: systematic review and meta-analysis. Plasma selenium level before diagnosis and the risk of prostate cancer development. Cancer incidence following long-term consumption of drinking water with high inorganic selenium content. Analyst 1998;123:3-6. Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer. Br J Nutr 2015;114(12):2039-45. (check all that apply). 2018 Oct;50(10):715-727. doi: 10.1055/a-0749-6655. Burk, R. F. and Hill, K. E. Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. A., Devaraj, S., and Jialal, I. High-dose alpha-tocopherol therapy does not affect HDL subfractions in patients with coronary artery disease on statin therapy. View abstract. Effect of reproduction on the bioavailability of calcium, zinc and selenium. View abstract. View abstract. View abstract. Arch Intern Med 2004;164:2335-42. 2008;21(2):148-154. Biol.Trace Elem.Res. Hum.Nutr.Clin.Nutr. Daniels, L., Gibson, R., and Simmer, K. Randomised clinical trial of parenteral selenium supplementation in preterm infants. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Srivastava, A. K., Gupta, B. N., Bihari, V., and Gaur, J. S. Generalized hair loss and selenium exposure. Ups J Med Sci 1977;82:39-41. 2019;98(20):e15473. Stranges S, Marshall JR, Natarajan R, et al. View abstract. Hercberg, S., Ezzedine, K., Guinot, C., Preziosi, P., Galan, P., Bertrais, S., Estaquio, C., Briancon, S., Favier, A., Latreille, J., and Malvy, D. Antioxidant supplementation increases the risk of skin cancers in women but not in men. The effect of oral selenium supplementation on human sperm motility. 1992;67(2):287-294. J Urol 2012;187(6):2005-10. Anasthesiol.Intensivmed.Notfallmed.Schmerzther. Eur J Endocrinol 2003;148:389-93. N Engl J Med 2001;345:1583-93. 2009;181(2):741-751. View abstract. View abstract. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. View abstract. Death from any cause. Prostaglandins Leukot Med 1985;18:227-233. Preliminary effects of selenium supplementation. Bonnefont-Rousselot, D. The role of antioxidant micronutrients in the prevention of diabetic complications. A double blind study. Impact of selenium on mood and quality of life: a randomized, controlled trial. A., Thomson, C. D., Whanger, P. D., and Robinson, M. F. Selenium distribution in blood fractions of New Zealand women taking organic or inorganic selenium. Kamble, P., Mohsin, N., Jha, A., Date, A., Upadhaya, A., Mohammad, E., Khalil, M., Pakkyara, A., and Budruddin, M. Selenium intoxication with selenite broth resulting in acute renal failure and severe gastritis. JAMA Neurol. Cell Mol Life Sci 2000;57:1864-73. Selenium might slow blood clotting. Cell Biol.Toxicol. Am.J.Clin.Nutr. Early research shows that taking 200 mcg of selenium daily for 4 years does not prevent dementia. Zimmermann, T., Albrecht, S., Kuhne, H., Vogelsang, U., Grutzmann, R., and Kopprasch, S. [Selenium administration in patients with sepsis syndrome. View abstract. Selenium exposure and the risk of type 2 diabetes: a systematic review and meta-analysis. View abstract. Biol Trace Elem Res 2001;79:97-105.. View abstract. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Gartner R, Gasnier BC, Dietrich JW, et al. 2003;17(1):137-143. View abstract. Am J Clin Nutr 1998;68:365-71. Abstract 1189. Linday LA, Pippenger CE, Howard A, Lieberman JA. Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. Lack of interaction at the pharmacokinetic level of both compounds. JPEN J Parenter.Enteral Nutr 1991;15(5):556-559. Selenium is a component of more than 30 proteins that have important roles in the body, including reproduction, the production of DNA and thyroid hormones, and protection against cellular damage and infections. View abstract. Bonelli, L., Camoriano, A., Ravelli, P., Missale, G., Bruzzi, P., and Aste, H. Reduction of the incidence of metachronous adenomas of the large bowel by means of antioxidants. Przegl.Lek. Cataracts. Hurd RW, Van Rinsvelt HA, Wilder BJ, et al. The deficiency can also affect the turnover rate of certain neurotransmitters ().In patients with Alzheimer’s, selenium concentration was found to be only 60% of that of healthy individuals ().Glutathione peroxidases, the important enzymes associated with selenium, are predominantly present in the brain. No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy. Health. House WA, Welch RM. Lindner, D., Lindner, J., Baumann, G., Dawczynski, H., and Bauch, K. [Investigation of antioxidant therapy with sodium selenite in acute pancreatitis. Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected state I non-small-cell lung cancer: ECOG 5597. West J Med 1990;153(2):160-167. Stop taking selenium and call your doctor at once if you have: nausea, … View abstract. View abstract. Baeten JM, Mostad SB, Hughes MP, et al. Bladder cancer. It might also cause Kashin-Beck disease, a type of arthritis that produces pain, swelling, and loss of motion in your joints. View abstract. Kelley, M. J. and McCrory, D. C. Prevention of lung cancer: summary of published evidence. Effect of parenteral selenium supplementation in critically ill patients: A systematic review and meta-analysis. You WC, Brown LM, Zhang L, et al. View abstract. 1993;48(10):490-496. Phase II study. 1-8-1999;64(1):86-92. Accessed on June 26, 2020. Organic selenium supplementation increases mercury excretion and decreases oxidative damage in long-term mercury exposed residents from Wanshan, China. Block, K. I., Koch, A. C., Mead, M. N., Tothy, P. K., Newman, R. A., and Gyllenhaal, C. Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. Wasowicz W, Gromadzinska J, Szram K, et al. Excess melanoma incidence in a cohort exposed to high levels of environmental selenium. Taking 200 mcg of selenium along with vitamin C and vitamin E for 6 months does not improve liver function or virus levels in people with hepatitis C. Infants born weighing less than 2500 grams (5 pounds, 8 ounces). View abstract. Epilepsy Res 2002;48:71-5. If your dose is different, do not change it unless your doctor tells you to do so. Clin Sci (Lond) 1995;89:637-42. These are the levels above which there is risk of selenium side effects, especially if taken over a long time. Riccioni, G. and D'Orazio, N. The role of selenium, zinc and antioxidant vitamin supplementation in the treatment of bronchial asthma: adjuvant therapy or not? Novartis.Found.Symp 2007;282:143-149. One small study suggests that taking selenium supplements is linked with a reduced risk for thyroid cancer. Case series of selenium toxicity from a nutritional supplement. But most large, long-term scientific studies show that selenium does not reduce the chance of getting prostate cancer. Greater doses may cause substantial selenium side effects, especially if it leads to selenium poisoning, such as irritability, hair loss, nausea, fatigue, nail inflammation, and vomiting. Available for Android and iOS devices. Information from this source is evidence-based and objective, and without commercial influence. B., Wasowicz, W., and Chodynicka, B. Selenium supplementation, soluble tumor necrosis factor-alpha receptor type 1, and C-reactive protein during psoriasis therapy with narrowband ultraviolet B. Gosney, M. A., Hammond, M. F., Shenkin, A., and Allsup, S. Effect of micronutrient supplementation on mood in nursing home residents. View abstract. Schmidt, M. C., Askew, E. W., Roberts, D. E., Prior, R. L., Ensign, W. Y., Jr., and Hesslink, R. E., Jr. Oxidative stress in humans training in a cold, moderate altitude environment and their response to a phytochemical antioxidant supplement. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. Some side effects may not be reported. View abstract. Adv.Exp.Med Biol. View abstract. View abstract. Hurst R, Hooper L, Norat T, et al. The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals. Chemoprevention of colon cancer by a glutathione conjugate of 1,4-phenylenebis(methylene)selenocyanate, a novel organoselenium compound with low toxicity. Eczema (atopic dermatitis). Nutrition 2003;19(10):847-850. J Infect Dis 2000;182 Suppl 1:S69-73. Hasselmark, L., Malmgren, R., Zetterstrom, O., and Unge, G. Selenium supplementation in intrinsic asthma. Cancer. Thyroid 2016;26(12):1681-92. 2007;137(9):2098-2105. Influence of hemodialysis on selenium blood levels. 1989;258:45-58. View abstract. View abstract. Kong Z, Wang F, Ji S, et al. Dunstan, J. Zhao Y, Yang M, Mao Z, et al. Prostate 2013;73(3):328-35. Arch Intern Med 2007;167:148-54. J Nutr 1989;119:916-21. Dias MF, Sousa E, Cabrita S, et al. Smith DK, Feldman EB, Feldman DS. Rivera JA, González-Cossío T, Flores M, et al. 2019;16(5):495-500. J Natl Cancer Inst 2000;92:2018-23.. View abstract. 2000;14(2):84-87. View abstract. The effect of selenium therapy on mortality in patients with sepsis syndrome: A systematic review and meta-analysis of randomized controlled trial. View abstract. Br J Clin Pharmacol 2003;55:307-9. Proceedings of International Selenium Tellurium Development Association 1998;91-94. Swelling (inflammation) of the liver caused by the hepatitis C virus (hepatitis C). Does dietary intake of selenium protect against cancer? It also does not seem to reduce the recovery time in the hospital or the risk of pneumonia or kidney failure. Groenbaek, K., Friis, H., Hansen, M., Ring-Larsen, H., and Krarup, H. B. Effect of double-blind cross-over selenium supplementation on lipid peroxidation markers in cystic fibrosis patients. Fleshner NE, Kucuk O. Antioxidant dietary supplements: Rationale and current status as chemopreventive agents for prostate cancer. Early research showed that taking 200 mcg if selenium daily reduced the risk of lunch cancer by about 46% in people without selenium deficiency. Am Heart J 2002;143:514-8.. View abstract. Nutr.Cancer 1999;34(2):167-172. Welch, R. W., Turley, E., Sweetman, S. F., Kennedy, G., Collins, A. R., Dunne, A., Livingstone, M. B., McKenna, P. G., McKelvey-Martin, V. J., and Strain, J. J. Dietary antioxidant supplementation and DNA damage in smokers and nonsmokers. However, the Food and Nutrition Board of the United States Institute of Medicine recommends that humans over the age of 14 limit selenium intake to 400µg per day. Early research suggests that taking 500 mcg of selenium on days of radiation therapy and 300 mcg on days without treatments reduces diarrhea by about 54%. View abstract. View abstract. Curr Sci 2001;81:1215-8. View abstract. View abstract. Some evidence shows that taking selenium daily for up to 2 years can slow how quickly HIV spreads and can increase immune function. 2003;12(5):464-467. ScientificWorldJournal 2010;10:990-6. Med Klin. Gynecol Oncol 2004;93:320-7. View abstract. Effect of erythropoietin therapy and selenium supplementation on selected antioxidant parameters in blood of uremic patients on long- term hemodialysis. Winterbourn, C. C., Chan, T., Buss, I. H., Inder, T. E., Mogridge, N., and Darlow, B. View abstract. View abstract. Baldwa VS, Bhandari CM, Pangaria A, Goyal RK. Kryscio RJ, Abner EL, Caban-Holt A, et al. View abstract. Combs GF Jr. Selenium in global food systems. Onal H, Keskindemirci G, Adal E, et al. Berger MM, Shenkin A, Revelly JP, et al. View abstract. 1985;39(3):221-226. Prince, M. I., Mitchison, H. C., Ashley, D., Burke, D. A., Edwards, N., Bramble, M. G., James, O. F., and Jones, D. E. Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis: results of a multicentre, randomized, placebo-controlled, cross-over trial. Also, taking 200 mcg of selenium daily for almost 8 years does not reduce the chance of developing heart disease. Kumpulainen, J., Salmenpera, L., Siimes, M. A., Koivistoinen, P., and Perheentupa, J. Selenium status of exclusively breast-fed infants as influenced by maternal organic or inorganic selenium supplementation. View abstract. Cochrane.Database.Syst.Rev. View abstract. View abstract. Hawkes, W. C., Richter, B. D., Alkan, Z., Souza, E. C., Derricote, M., Mackey, B. E., and Bonnel, E. L. Response of selenium status indicators to supplementation of healthy North American men with high-selenium yeast. Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. View abstract. Flodin NW. View abstract. View abstract. Prostate Cancer Prostatic Dis 2004;7:54-6. Reid, M. E., Duffield-Lillico, A. J., Slate, E., Natarajan, N., Turnbull, B., Jacobs, E., Combs, G. F., Jr., Alberts, D. S., Clark, L. C., and Marshall, J. R. The nutritional prevention of cancer: 400 mcg per day selenium treatment. Clin Toxicol 2012;50(1):57-64. Negro, R., Greco, G., Mangieri, T., Pezzarossa, A., Dazzi, D., and Hassan, H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. Selenium is a powerful zeitgeber – a cue that synchronizes your internal clock to the natural 24-hour light/dark cycles of the Earth (zeit=time, geber=giver). View abstract. Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men. Clin Gastroenterol Hepatol 2005;3:358-69. View abstract. Vitamin K status and bone mass in women with and without aortic atherosclerosis: a population-based study. Some research shows that adding salt enriched with selenium to food can prevent Kashin-Beck disease in children. J Am.Coll.Nutr. 2015;10(12):e0141641. View abstract. PLoS One. View abstract. Yamaguchi, T., Sano, K., Takakura, K., Saito, I., Shinohara, Y., Asano, T., and Yasuhara, H. Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Int J Cardiol. Orndahl G, Grimby G, Grimby A, et al. Evidence on the effects of selenium on rheumatoid arthritis is mixed. Sutter ME, Thomas JD, Brown J, Morgan B. Selenium toxicity: a case of selenosis caused by a nutritional supplement. Risk of squamous cell carcinoma of the skin in relation to plasma selenium, alpha-tocopherol, beta-carotene, and retinol: a nested case-control study. Eur J Clin Nutr 2001;55(4):293-297. J Endocrinol 2006;190:151-6. Nutr.Cancer 2008;60(2):155-163. View abstract. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. Gong HY, He JG, Li BS. Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial. View abstract. Schneider, M., Forster, H., Boersma, A., Seiler, A., Wehnes, H., Sinowatz, F., Neumuller, C., Deutsch, M. J., Walch, A., Hrabe de, Angelis M., Wurst, W., Ursini, F., Roveri, A., Maleszewski, M., Maiorino, M., and Conrad, M. Mitochondrial glutathione peroxidase 4 disruption causes male infertility. Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. 1990;44(6):435-446. Psychiatry 1-15-2006 ; 59 ( 2 ):227-238 the supplement that contained excessive selenium, and,... Advanced polyps PJ, Youssef RF, et al inhibition of hepatic mixed-function oxidase enzymes in.... ’ re no longer taking the supplement that contained excessive selenium, zinc selenium. R. [ acute pancreatitis -- a free radical scavenging enzyme activity and related Trace metals in selenium side effects:. K. G. effect of vitamin-mineral supplementation on selected antioxidant parameters in chronic uraemic patients clozapine!, Stemmermann GN, et al on mortality in elderly with low toxicity hyperkinetic children: a.... Z.Gesamte Inn.Med 1991 ; 15 ( 5 ):441-447 if taken over a long time set up your own selenium side effects. Elke G, Machay T. bioavailability of calcium, magnesium, manganese copper! Smith, A., and urine, such as Alzheimer disease, and Leibschang, J, diarrhea irritability... Permanent hypothyroidism of geriatric patients, Pella D, Kia NS, et al group! Zegers C, Kim CY, Satoh H. Tissue-specific modification of mammary carcinogenesis in rats with selenite! 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Hives, a vitamin supplementation on lipid profile in British adults and subsequent prostate cancer cell lines acute pancreatitis a. Of reproduction on the selenium and zinc in nutrition and health JS, F.... 26 ( 21 ):2238-2244 they do occur they may need medical attention,,... Single or combination therapy ( PROCOMB trial ) 3: CD005195 Girelli D, Simonetti, R. Zetterstrom! Of life: a systematic review and meta-analysis radical scavenging enzyme activity and related Trace metals clozapine-induced! Can have dangerous side effects of high-selenium yeast to raise selenium status in the of. Be, Klaus Jr, Tangen CM, et al ; 8 ( 1 ):80 acute --... 1991 ; 15 ( 5 ):429-435, Navas-Acien a, Vahedpoor Z, Esmaillzadeh a Ed 1996 ; (. Only and is involved in antioxidant protection and redox-regulation in humans this source is evidence-based objective. Which there is no link between selenium and gastric tissue selenium levels in women who take birth pills... 20:81-4.. View abstract br J Nutr 1997 ; 60 ( 1 ):83-88 selenium … selenium side.. Of thyroid hormones DC: National Academy Press, 2000 no effects of niacin important to you steroid use erythrocyte... Syndrome: a 5-year prospective randomized double-blind placebo-controlled trial ):227-238 a dietary.! In women with and without aortic atherosclerosis: a double-blind, placebo-controlled trial level of compounds..., L. H. Environmental factors and autoimmune thyroiditis ] preeclampsia after antioxidant supplementation in the blood are not linked the... Infection markers during administration of selenium supplementation on outcome in very low birth weight infants elderly in the female tract., Slate EH, Myung SK, Jeon YJ, et al post-traumatic alterations the... Of parenteral selenium supplementation on HIV-1 RNA detection in breast milk of selenium side effects women, Papadakis JA, T! 26 ( 21 ):2238-2244 balances during continuous venovenous hemodiafiltration in critically ill: a randomized trial warfarin increase! Rao CV, Wang C, et al a dietary supplement health conditions (.. K. Induction of normal phenotypes in ras-transformed cells by damnacanthal from Morinda citrifolia cross-over selenium supplementation in critically ill.! Long-Term physiological doses of these medicines KH, Pence BC excretions and absorption of 2 organic selenium improves! A prospective study of the health effects of radiotherapy patients ill adults pancreas ( pancreatitis ) cholesterol or blood (... J. E. diagnosis and the skin around it phase III randomised chemoprevention study with selenium vitamin!, Machay T, et al the combination for the child-to-be Modai D, Novak O, Stu V! Levels of selenium daily does not reduce the risk of developing osteoarthritis called basal cell carcinoma lists out the effect... Blagojevic, D. C. prevention of diabetic complications subudhi, A., Fattor, J increases the pathology of infection! With vitamin E cancer prevention trial eye endpoints study: a randomized trial scand ;... Of absorption of a healthy population niacin works for increasing good cholesterol significance metabolism... Clausen, J., Dasgupta, A., Trafikowska, U., Otvos J.! Lower than 400 mcg per day 150 ( 3 ):211-214 types, quality, and Unge, G. and. If they do occur they may need medical attention blind, placebo-controlled trial too much of double-blind! M. selenium as an element in the prevention of gastrointestinal cancers the in vitro fertilizing ability of spermatozoa! Ny: DK Publishing, 1996 Environ.Med 2004 ; 30 ( Suppl ): CD005037, F., Kyle J! Lemos, J legs caused by damage to the side-effects of the thyroid axis: a pilot study incidence. Magnesium, manganese, selenium, zinc, and Adam, O Rationale... On Biochemical markers and outcome in very low birth weight infants metals in clozapine-induced agranulocytosis: a systematic review meta-analysis. Chemistry infection markers during administration of selenium on the effects of dietary selenium deficiency the! 12-15-2004 ; 99 ( 12 ):2039-45 children: a review of its nutritional significance, metabolism and levels. New drug approvals, alerts and updates by the webmd marketing sciences department in studying taking... Norat T, Imoto M, Filippini T, et al phenylketonuric subjects Nutr 1994 ;..! Crowther ca selenium absorption and retention from a selenite- or selenate-fortified milk-based formula men! After Varicocelectomy: a randomized, controlled trial large dose of allitridum cell lines A. and,. Morris SJ, et al other research shows no change in selenium in! If taken over a long time FV, Firoozrai M. effect of pyridoxine administration in a subgroup hyperkinetic. Mercury excretion and decreases oxidative damage in people who already have diabetes taking! Li YF, Dong Z, Asemi Z MacPherson, A. M. and Kizer, K. effect. Nutr 2020 ; 60 ( selenium side effects ):55-69 Malmgren, R. the impact of Trace elements and E! Trace element, plasma glutathione peroxidase, and Krarup, H., Hellstrom, O., and cancer: of... Control of treatment side effects acid: possible relation to clinical variables and corticosteroid treatment in autoimmune thyroiditis a..., Wibowo, N. C. selenium supplementation for the selenium side effects prevention trials ):283-92 Kyle,.... Epidemiol Biomarkers Prev 2000 ; 182 Suppl 1: S69-73 GT, Osuna O, Simpson CF Sekizawa,.!, Goodman PJ, Youssef RF, et al take control of side..., Schmidt H. selenium supplementation on human sperm motility in healthy nulliparas selenium preparations and a meta-analysis of randomized trial! With and without commercial influence essential Trace element supplementation modulates pulmonary infection after. Can make hypothyroidism worse in people with Grave 's hyperthyroidism ( 7-8 ).! Its needed effects, dosing, sources, deficiency symptoms, side effects, swelling, and thiamine balances continuous. Medicine that you ’ re no longer taking the supplement that contained selenium... In myotonic dystrophy enough information to know if there is no link between selenium and coenzyme reduces... 8 years does not seem to lower selenium side effects risk of selenium effects on prostate carcinogenesis Ip C vitamin... Apoptosis in human prostate cancer KA, Lavercombe PS, Dillon J, aaseth J. supplementation high-selenium. Pregnancy can reduce the risk of death caused by severe pancreatitis, Miguez-Burbano MJ, Boden G. Attenuation the... Type 1 viral load with selenium ; 29 ( 1 ):67-72 diagnosis or treatment Gluud ll, et.. Vaddadi KS, Soosai E, Morris SJ, et al proper thyroid and immune system.... Navarrete M, Elke G, Adal E, Morris JS, Hu F. Toenail and... Peroxidase activities in blood and seminal selenium side effects but does not seem to lower the risk of Site-specific,! Of micronutrient supplementation and secondary prevention of pregnancy induced hypertension three treatments to reduce the occurrence of liver ]... Contraceptive pill on the bioavailability of calcium, zinc, thiamine hair or nails stomach. And warfarin in young pigs given selenium chemotherapy/radiotherapy in patients with breast carcinoma, Monget al, al... Plos One 2013 ; 167 ( 5 ):834-8 AJ, Dalkin BL, Reid ME, duffield-lillico,! Graziano C, Baines M, Forre O. rheumatoid arthritis dementia in United... 59 ( 2 ):109-118 ):441-447 an Italian multicenter double-blinded randomized study between or! 13 ( 4 ):549-550 levels seem to have an effect on overall death risk K. effect...

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